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KMID : 0388220130200050328
Journal of the Korean Rheumatism Association
2013 Volume.20 No. 5 p.328 ~ p.331
A Case of Rheumatoid Arthritis with Chronic Eosinophilic Pneumonia Associated with Eosinophilic Pleural Effusion


Jee Yong-Gwan
Park Yu-Mi
Cha Jae-Hwang
Kang Yong-Seok
Park Jeong-Ha
Kang Tae-Young
Abstract
We describe a 48-year-old man with family history of rheumatoid arthritis (RA) affected by chronic eosinophilic pneumonia (CEP) with severe peripheral eosinophilia. CEP might develop as a complication of longstanding ac-tive RA. The patient with 5 months history of seropositive RA and chronic respiratory symptoms, alveolar and blood eosinophilia, peripheral pulmonary infiltrates and pleural effusion on chest imaging. The lung may be involved as an extraarticular manifestation of RA. However, CEP is not recognized as a typical lung manifestation of RA, and the two diseases rarely coexist. The effusion was an eosino-phil predominant exudates and was characterized by low pH, and glucose level and high lactic dehydrogenase. The patient responded rapidly to combination of steroids and disease modifying anti-rheumatic drugs.
KEYWORD
Rheumatoid arthritis , Chronic eosinophilic pneumonia , Pleural effusion
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